Methylation of Selenocysteine (cas 10236-58-5) catalysed by thiopurine S-methyltransferase
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Add time:07/24/2019 Source:sciencedirect.com
BackgroundMethylation driven by thiopurine S-methylatransferase (TPMT) is crucial for deactivation of cytostatic and immunosuppressant thiopurines. Despite its remarkable integration into clinical practice, the endogenous function of TPMT is unknown.
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