Toxicology, metabolism, and biochemistry of 1,2-propanediol
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Add time:07/25/2019 Source:sciencedirect.com
The toxicity of 1,2-propanediol is reviewed, and a table of the LD50 values for the rat, rabbit, mouse, guinea pig, and dog is presented. Metabolic and chronic studies demonstrate that 1,2-propanediol can be used as a substitute for carbohydrate in the diet of rats and young chicks. The glycol is primarily oxidized to lactate or pyruvate.
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