Debromination of 8-bromo-2′-deoxyguanosine by methylene blue and visible light

Add time:07/25/2019    Source:sciencedirect.com

Debromination of 8-bromo-2′-deoxyguanosine was accomplished in high yield under neutral conditions in aqueous methanol by irradiating with visible light in the presence of methylene blue as a sensitizer and triethylamine as an electron donor. The method can be extended for the debromination of other bromoaromatic compounds.

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