8-Amino-2′-deoxyadenosine:2′-Deoxythymidine Base Pairing: Identification of Novel Reverse Hoogsteen Mode in Solution
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Add time:07/26/2019 Source:sciencedirect.com
A novel reversed Hoogsteen mode is observed for the base-pairing of 8-amino-2′-deoxyadenosine with 2′-deoxythymidine in low dielectric solvent. The results may have important significance for designing novel DNA duplexes and triplexes incorporating 8-amino-dA.
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