A novel, three-component reaction to the synthesis of 3-amino-4-cyano-5-aryl-1H-pyrrole-2-carboxamides
-
Add time:07/11/2019 Source:sciencedirect.com
This work described a novel and efficient synthesis of 3-amino-4-cyano-5-phenyl-1H-pyrrole-2-carboxamides. The synthesis was carried out via a simple three-component reaction between arylidenmalononitrile, malononitrile and hydroxylamine hydrochloride in solvent-free conditions. Short reaction times, good to excellent yields of products, inexpensive and readily available starting material, and time and energy saving are the main advantages of this method. The structures of the products were confirmed by 1HNMR, 13CNMR, IR and single crystal X-ray analysis.
We also recommend Trading Suppliers and Manufacturers of 3-amino-4-(4-chlorophenyl)-N-(3-methylphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (cas 337489-05-1). Pls Click Website Link as below: cas 337489-05-1 suppliers
Prev:Aromatic β-amino-ketone derivatives as novel selective non-steroidal progesterone receptor antagonists
Next:Investigating structure–activity relationship and mechanism of action of antitubercular 1-(4-chlorophenyl)-4-(4-hydroxy-3-methoxy-5-nitrobenzylidene) pyrazolidine-3,5-dione [CD59]) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Synthesis and structural identification of 5-amino-4-hydroxyiminopyrazoles and (E)-N1-aryl-3-aryl-4-[(substituted pyrazolyl)diazenyl] pyrazoles from 5-aminopyrazoles with ethyl nitrite or sodium nitrite07/14/2019
- Discovery of 4-amino-3-arylsulfoquinolines, a novel non-acetylenic chemotype of metabotropic glutamate 5 (mGlu5) receptor negative allosteric modulators07/13/2019
- Investigating structure–activity relationship and mechanism of action of antitubercular 1-(4-chlorophenyl)-4-(4-hydroxy-3-methoxy-5-nitrobenzylidene) pyrazolidine-3,5-dione [CD59]07/12/2019
