Synthesis and Hypotensive Properties of 4-Amino-6,7-Dimethoxyisoquinoline

Add time:07/27/2019    Source:sciencedirect.com

The compound 4-amino-6,7-dimethoxyisoquinoline hy-drochloride, a structural isomer of amiquinsin hydrochloride (4-amino-6,7-dimethoxyquinoline hydrochloride), was synthesized. It was shown to be hypotensive in anesthetized normotensive dogs and produced an antihypertensive effect in unanesthetized renal hypertensive dogs.

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