Iron(III) chloride-catalyzed synthesis of 3-carboxy-2,5-disubstituted furans from γ-alkynyl aryl- and alkylketones

Add time:07/27/2019    Source:sciencedirect.com

A mild, catalytic method for the synthesis of 3-carboxy-2,5-disubstituted furans is reported proceeding via a 5-exo-dig cycloisomerization reaction. The iron(III) chloride-catalyzed transformation of aryl- and alkyl β-ketoesters enables synthetic access to functionalized furan core structures found in many natural products and complex molecules of biological importance. The method described herein, represents a mild and efficient alternative to currently available reaction protocols.

We also recommend Trading Suppliers and Manufacturers of 2-hydroxy-3-methylbenzoyl chloride (cas 15198-07-9). Pls Click Website Link as below: cas 15198-07-9 suppliers

Prev:The hydrolysis of succinyldithiocholine (cas 15196-10-8) and related thiocholine esters by human plasma and purified cholinesterase
Next:Anticoagulant and antithrombotic effects of chemically sulfated fucogalactan and citrus pectin)