Synthesis and biological evaluation of a small library of Nojirimycin (cas 15218-38-9)-derived bicyclic iminosugars

Add time:07/27/2019    Source:sciencedirect.com

Novel nojirimycin-derived bicyclic structures, containing cyclic carbamate, urea and guanidine moieties have been synthesised starting from suitably protected α-C-vinylnojirimycin and α-C-allylnojirimycin, respectively, and their biological activity against different glycosidases and as antibacterial agents tested.

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