Synthesis of dibenzo[d,f]diazepinones and alkenylindolinones through ring transformation of 2H-pyran-2-one-3-carbonitriles by indolin-2-ones

Add time:07/28/2019    Source:sciencedirect.com

First ever synthesis of functionalized 5,7-dihydro-6H-dibenzo[d,f][1,3]diazepin-6-ones (6, 9) has been developed through base induced ring transformation of 2H-pyran-2-one-3-carbonitriles with indolin-2-ones. A protocol for alkenylating indolin-2-ones by 2H-pyran-2-one-3-carbonitriles has also been developed to obtain 3-alkenylindolin-2-ones (11). The nature and behaviour of intermolecular interactions of these compounds are studied by single crystal-X-ray analysis and quantum chemical calculations.

We also recommend Trading Suppliers and Manufacturers of 3(2H)-Isoxazolone,5-(4-piperidinyl)-(9CI) (cas 132033-91-1). Pls Click Website Link as below: cas 132033-91-1 suppliers

Prev:Synthesis and characterization of novel 6-fluoro-4-piperidinyl-1,2-benzisoxazole amides and 6-fluoro-chroman-2-carboxamides: antimicrobial studies
Next:Synthesis and structure–activity relationships study of cytotoxic bufalin 3-nitrogen-containing-ester derivatives)