Synthesis of Chromeno[3,4-c]pyridines by Rhodium(III)-Catalyzed annulation of coumarinyl ketoxime esters and alkynes

Add time:07/29/2019    Source:sciencedirect.com

An efficient, scalable synthetic method of chromeno[3,4-c]pyridine scaffolds through redox-neutral [4 + 2] annulation between coumarinyl ketoxime esters and internal alkynes has been developed using the rhodium(III) catalytic system. The present transformation proceeds under mild conditions, features good functional group compatibility and obivates the use of external oxidants. Ready access to pyridine derivatives bearing three carbon substituents is exemplified.

We also recommend Trading Suppliers and Manufacturers of 2-(3-METHOXY-PHENYL)-OXAZOLE-4-CARBOXYLIC ACID ETHYL ESTER (cas 132089-44-2). Pls Click Website Link as below: cas 132089-44-2 suppliers

Prev:Synthesis, characterization and antimicrobial studies of 2-(4-methoxy-phenyl)-5-methyl-4-(2-arylsulfanyl-ethyl)-2,4-dihydro-[1,2,4] triazolo-3-ones and their corresponding sulfones
Next:Analytical method for the trace determination of esterified 3- and 2-monochloropropanediol and glycidyl fatty acid esters in various food matrices)