Building block synthesis of predominantly (E) symmetrical and unsymmetrical 1,2-difluorostilbenes from 1,2-dibromo-1,2-difluoroethene

Add time:07/28/2019    Source:sciencedirect.com

An efficient synthesis of predominantly (E) symmetrical or unsymmetrical 1,2-difluorostilbenes based on the Suzuki–Miyaura palladium-catalyzed cross-coupling reaction of arylboronic acids with predominantly (E)-1,2-dibromo-1,2-difluoroethene in the presence of Cs2CO3 in toluene is described. The reaction preserved the stereochemistry of the building block and performed in good yield independently of the electron-withdrawing or electron-donating character of the substituents.

We also recommend Trading Suppliers and Manufacturers of BENZENE,1,1'-(1,2-ETHENEDIYL) (cas 10311-74-7). Pls Click Website Link as below: cas 10311-74-7 suppliers

Prev:Cadmium(II) complexes containing N′-substituted N,N-di(2-picolyl)amine: The formation of monomeric versus dimeric complexes is affected by the N′-substitution group on the amine moiety
Next:Occurrence and exposure of 3-monochloropropanediol diesters in edible oils and oil-based foodstuffs from the Spanish market)