Synthesis and in vitro cytotoxicity of cis-(glycolato-O,O′)-[2-substituted-(4R,5R)-4,5-bis(aminomethyl)-1,3-dioxolane]platinum (II)

Add time:07/28/2019    Source:sciencedirect.com

The synthesis and in vitro cytotoxicity of cis-(glycolato-O,O′)[2-substituted-(4R,5R)-4,5-bis(aminomethyl)-1,3-dioxolane]platinum(II) are described. Among them, cis-(glycolato-O,O′)[(4R,5R)-4,5-bis(aminomethyl)-2,2-diethyl-1,3-dioxolane]platinum(II) (26) was found to be almost equally cytotoxic to cisplatin against two human non-small cell lung cancer cell lines, PC-9 and PC-14, and two human stomach cancer cell lines, MKN-45 and KATO III.

We also recommend Trading Suppliers and Manufacturers of cis-1,3-Bis(aMinoMethyl)cyclohexane (cas 10340-00-8). Pls Click Website Link as below: cas 10340-00-8 suppliers

Prev:The fatty acids of calcareous sponges (Calcarea, Porifera)
Next:Cost effective thermoelectric composites from recycled carbon fibre: From waste to energy)