Synthesis and evaluation of a new series of 17α-[123I]iodovinyl estradiols
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Add time:07/31/2019 Source:sciencedirect.com
A series of 17α-substituted estradiols was synthesized in which the stereochemical characteristics of carbons 20 and 21 were modified. It was found that the (Z)-isomer demonstrated more favorable receptor binding affinity than the corresponding (E)-isomer.
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