Investigations into carbamate insecticide selectivity

Add time:07/29/2019    Source:sciencedirect.com

Investigations were made of the effects of various modifications of the ether moiety alkoxyiminomethylphenyl N-methylcarbamates on the selective toxicity of the compounds to mouse vs. housefly. The highest mammalian selectivity ratio was found with o-(isopropyloxyiminomethyl)-phenyl N-methylcarbamate which was about 30-fold more toxic to fly than to mouse. The o-(1-propynyloxyiminomethyl)-phenyl N-methyl-carbamate was the most toxic compound to the housefly. The biochemcial basis for selective action was investigated.

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