Solid phase strategies: Applications of 2-acetyl-4-nitroindane-1,3-dione as a selective protecting group for primary amines

Add time:07/29/2019    Source:sciencedirect.com

2-Acetyl-4-nitroindane-1,3-dione (1) has been successfully exploited as a primary amine protecting group displaying excellent acid and secondary/tertiary base stability, but which can be removed with 2% hydrazine at ambient temperature. (1) has been condensed with both amino acids and spermidine, affording derivatives which were subsequently utilised in the solid phase synthesis of various peptides and the glutathione-spermidine conjugate trypanothione respectively.

We also recommend Trading Suppliers and Manufacturers of H-LYS-OBZL 2 P-TOSYLATE (cas 16259-78-2). Pls Click Website Link as below: cas 16259-78-2 suppliers

Prev:Étude de la pénimocycline par chromatographie en phase liquide à haute performance
Next:The structure of a triclinic form of Octafluoroselenanthrene (cas 16259-99-7), (C6F4)2Se2)