NBS-mediated practical cyclization of N-acyl amidines to 1,2,4-oxadiazoles via oxidative N‒O bond formation
-
Add time:07/13/2019 Source:sciencedirect.com
A reaction involving an efficient NBS-mediated oxidative N‒O bond formation has been established for the synthesis of 1,2,4-oxadiazoles from readily accessible N-acyl amidines. The features of this synthetic method include simplicity of operation, mild reaction conditions, short reaction times, high yields, and eco-friendliness. The reaction also works well with crude N-acyl amidines obtained by amidation of simple benzoic acids and amidines to produce biologically relevant 1,2,4-oxadiazoles in a scalable fashion.
We also recommend Trading Suppliers and Manufacturers of N-(4-bromo-2-fluorophenyl)-2-methylpropanamide (cas 430467-94-0). Pls Click Website Link as below: cas 430467-94-0 suppliers
Prev:Inhibition of angiogenic tubule formation and induction of apoptosis in human endothelial cells by the selective cyclooxygenase-2 inhibitor 5-bromo-2-(4-fluorophenyl)-3-(methylsulfonyl) thiophene (DuP-697)
Next:N,N′-diaryl-bishydrazones in a biphenyl platform: Broad spectrum antifungal agents) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Microwave synthesis, characterization and antimicrobial study of new pyrazolyl-oxopropyl-quinazolin-4(3H)-one derivatives07/15/2019
- N,N′-diaryl-bishydrazones in a biphenyl platform: Broad spectrum antifungal agents07/14/2019
- Inhibition of angiogenic tubule formation and induction of apoptosis in human endothelial cells by the selective cyclooxygenase-2 inhibitor 5-bromo-2-(4-fluorophenyl)-3-(methylsulfonyl) thiophene (DuP-697)07/12/2019
- Synthesis of N-(4-bromo-2-trifluoromethylphenyl)-1-(2-fluorophenyl)-O,O-dialkyl-α-aminophosphonates under ultrasonic irradiation07/11/2019
