Synthesis, antibacterial and antifungal activities of some N-nitroso-2,6-diarylpiperidin-4-one semicarbazones and QSAR analysis
-
Add time:08/01/2019 Source:sciencedirect.com
A series of N-nitroso-2,6-diarylpiperidin-4-one semicarbazones and thiosemicarbazones were synthesized, characterized by IR, NMR and elemental analysis. All the compounds were screened for their antibacterial activity against Gram-positive bacteria Bacillus subtilis, Staphylococcus aureus and Gram-negative bacteria Escherichia coli and fungi Candida albicans. These compounds have showed moderate and very good antibacterial activity. Quantitative Structure Activity Relationship (QSAR) analysis was performed for these compounds by the application of Semiempirical calculations and molecular modeling. Different log P values were also evaluated to further the analysis.
We also recommend Trading Suppliers and Manufacturers of (3E)-4-[(R)-2,2,6-Trimethyl-5-cyclohexen-1-yl]-3-buten-2-one semicarbazone (cas 109963-38-4). Pls Click Website Link as below: cas 109963-38-4 suppliers
Prev:Metal complexes of a pentadentate N2O3 bis(semicarbazone) Schiff-base. A case study of structure-spectroscopy correlation
Next:Anticonvulsant properties of various acetylhydrazones, oxamoylhydrazones and semicarbazones derived from aromatic and unsaturated carbonyl compounds) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Selective and potent monoamine oxidase type B inhibitors: substituted semicarbazones and acylhydrazones of aromatic aldehydes and ketones08/07/2019
- Synthesis and biological evaluation of phenolic Mannich bases of benzaldehyde and (thio)semicarbazone derivatives against the cysteine protease falcipain-2 and a chloroquine resistant strain of Plasmodium falciparum08/06/2019
- Synthesis and anti-trypanosomal activity of novel 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives08/05/2019
- Some aryl semicarbazones possessing anticonvulsant activitie08/04/2019
- EPR, mass, IR, electronic, and magnetic studies on copper(II) complexes of semicarbazones and thiosemicarbazones08/03/2019
- Anticonvulsant properties of various acetylhydrazones, oxamoylhydrazones and semicarbazones derived from aromatic and unsaturated carbonyl compounds08/02/2019
- Metal complexes of a pentadentate N2O3 bis(semicarbazone) Schiff-base. A case study of structure-spectroscopy correlation07/31/2019
- Synthesis and preliminary screening for the biological activity of some steroidal Δ4-unsaturated semicarbazone derivatives07/30/2019
