Naringin promotes fracture healing through stimulation of angiogenesis by regulating the VEGF/VEGFR-2 signaling pathway in osteoporotic rats

Add time:08/01/2019    Source:sciencedirect.com

Postmenopausal osteoporosis is characterized by a reduction in the number of sinusoidal and arterial capillaries in the bone marrow and reduced bone perfusion. Thus, osteogenesis and angiogenesis are coupled in the process of osteoporosis formation and fracture healing. Naringin is the main ingredient of the root Rhizoma Drynariae, a traditional Chinese medicine, and it has potential effects on promoting fracture healing. However, whether naringin stimulates angiogenesis in the process of bone healing is unclear. Here, we show that naringin promotes fracture healing through stimulating angiogenesis by regulating the VEGF/VEGFR-2 signaling pathway in osteoporotic rats.

We also recommend Trading Suppliers and Manufacturers of NARINGIN HYDRATE TECH. (cas 132203-74-8). Pls Click Website Link as below: cas 132203-74-8 suppliers

Prev:Effects of Cilnidipine (cas 132203-70-4) on sympathetic nerve activity and cardiorenal function in hypertensive patients with type 2 diabetes mellitus: Association with BNP and aldosterone levels
Next:Synthesis and structure–activity relationships of 1-benzylindane derivatives as selective agonists for estrogen receptor beta)