A novel synthesis of 9-cis-retinoic acid and tagretin analogues via the Pauson–Khand or Heck reaction

Add time:08/01/2019    Source:sciencedirect.com

The synthesis of a selection of compounds related to 9-cis-retinoic acid and tagretin is outlined. The methodology utilises the Pauson–Khand and Heck reaction as the key steps to prepare the intermediate aryl cyclopentenone regioisomers.

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