An efficient synthesis of fully substituted pyrazolo[3,4-b]pyridin-5-amines from α-azidochalcones

Add time:08/06/2019    Source:sciencedirect.com

A facile, mild and efficient procedure for the synthesis of fully substituted pyrazolo[3,4-b]pyridin-5-amines is reported. A mixture of an α-azidochalcone, a 5-aminopyrazole and t-BuOK was stirred in DMF at ambient temperature for 5 min to afford the corresponding pyrazolo[3,4-b]pyridin-5-amines in good to excellent yields.

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