Targeting hepatic miR-221/222 for therapeutic intervention of nonalcoholic steatohepatitis in mice
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Add time:08/02/2019 Source:sciencedirect.com
BackgroundEffective targeting therapies for common chronic liver disease nonalcoholic steatohepatitis (NASH) are in urgent need. MicroRNA-targeted therapeutics would be potentially an effective treatment strategy of hepatic diseases. Here we investigated the functional role of miR-221/222 and the therapeutic effects of antimiRs-221/222 in NASH mouse models.
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