Regioselective synthesis of trifluoromethylated 3-(pyrazolyl)indoles on the basis of 6-(trifluoromethyl)comanic acid

Add time:08/02/2019    Source:sciencedirect.com

A number of trifluoromethylated 3-(pyrazolyl)indoles was synthesized from 2-(trifluoromethyl)comanic acid, its ethyl ester and amide via intermediate isomeric 5(3)-[3,3,3-trifluoro-2-(phenylhydrazono)propyl]pyrazole-3(5)-carboxylic acids and their derivatives.

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