Synthesis and evaluation of 3-cyano-4-imino-2-methylthio-4H-pyrido[1,2-a]pyrimidine derivatives as potent antioxidant agents
-
Add time:08/03/2019 Source:sciencedirect.com
The bis (methylthio) methylene malononitrile (1) on treatment with 2-amino pyridine (2) in N,N-dimethyl formamide (DMF) and anhydrous potassium carbonate, gives 3-cyano-4-imino-2-(methylthio)-4H-pyrido[1,2-a]pyrimidine (3). The latter were further reacted with selected N-, O- and C-nucleophiles such as aryl amines, hetryl amines, substituted phenols and compounds containing active methylene groups.
We also recommend Trading Suppliers and Manufacturers of 4-(Methylthio)phenol (cas 1073-72-9). Pls Click Website Link as below: cas 1073-72-9 suppliers
Prev:(Methylthio)phenol semiochemicals are exploited by deceptive orchids as sexual attractants for Campylothynnus thynnine wasps
Next:Formation, characterization, aggregation, fluorescence and antioxidant properties of novel tetrasubstituted metal-free and metallophthalocyanines bearing (4-(methylthio)phenoxy) moieties) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Assessment of β-glucans, phenols, flavor and volatile profiles of hulless barley wine originating from highland areas of China08/09/2019
- Molecular docking studies and facile synthesis of most potent biologically active N-tert-butyl-4-(4-substituted phenyl)-2-((substituted-2-oxo-2H-chromen-4-yl)methylthio)-6-oxo-1,6-dihydropyrimidine-5-carboxamide hybrids: An approach for microwave-assisted syntheses and biological evaluation08/08/2019
- Synthesis and in-vitro anticancer activity of 3-cyano-6,9-dimethyl-4-imino 2-methylthio 4H-pyrimido [2,1-b] [1,3] benzothiazole and its 2-substituted derivatives08/07/2019
- 4-Methylthio-butanyl derivatives from the seeds of Raphanus sativus and their biological evaluation on anti-inflammatory and antitumor activities08/06/2019
- Synthesis of trifluoromethyl ethers and difluoro(methylthio)methyl ethers by the reaction of dithiocarbonates with IF5-pyridine-HF08/05/2019
- Formation, characterization, aggregation, fluorescence and antioxidant properties of novel tetrasubstituted metal-free and metallophthalocyanines bearing (4-(methylthio)phenoxy) moieties08/04/2019
- (Methylthio)phenol semiochemicals are exploited by deceptive orchids as sexual attractants for Campylothynnus thynnine wasps08/02/2019
