Novel preparation of N-arylmethyl-N-arylmethyleneamine N-oxides from benzylic bromides with zinc and isobutyl nitrite

Add time:08/03/2019    Source:sciencedirect.com

Treatment of benzylic bromides with Zn and LiCl, followed by the reaction with i-butyl nitrite gave N-arylmethyl-N-arylmethyleneamine N-oxides in moderate yields. The present reaction is a novel and simple method for the preparation of nitrones from benzylic bromides, although the yields are moderate.

We also recommend Trading Suppliers and Manufacturers of 4-BUTYLBENZYL BROMIDE (cas 10531-16-5). Pls Click Website Link as below: cas 10531-16-5 suppliers

Prev:The synthesis of (4R-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate, a key intermediate for the preparation of CI-981, a highly potent, tissue selective inhibitor of HMG-CoA reductase
Next:Friedel–Crafts alkylation of sodium salicylate with 4-tert butylbenzyl chloride performed in aqueous dispersions of mesoporous oxides)