Cobalt-catalyzed oxidative arylmethylation of phosphorylamides

Add time:08/03/2019    Source:sciencedirect.com

A cobalt-catalyzed strategy for N-arylmethylation of phosphorylamides was herein achieved with the assistance of azodiisobutyronitrile as the radical initiator and di-tert-butyl peroxide as the oxidant. Both methylarenes and diaryl methanes were compatible under the oxidative conditions, expressing broad substrate scope (51 examples) and high efficiency (up to 87% yield).

We also recommend Trading Suppliers and Manufacturers of (Cyclohexyloxy)boron oxide (cas 10534-18-6). Pls Click Website Link as below: cas 10534-18-6 suppliers

Prev:Biosynthesis of diaporthin (cas 10532-39-5) and orthosporin by Aspergillus ochraceus
Next:Design, synthesis and biological evaluation of 2′-deoxy-2′,2′-difluoro-5-halouridine phosphoramidate ProTides)