A general and efficient Pd-catalyzed rapid 2-fluoroethoxylation of bromo-chalcones

Add time:08/05/2019    Source:sciencedirect.com

An efficient unprecedented Pd-catalyzed rapid 2-fluoroethoxylation of bromo-chalcones has been unveiled. The oxygen nucleophiles (fluoroalcohols) experience the rapid CO bond forming reaction for the first time, albeit the alcohols are known to be a weak nucleophile and have greater competing β–hydride elimination in the transition-metal-catalyzed (especially Pd and Cu) CO cross-coupling reaction. The higher fluoroalcohols have also been effectively coupled with bromo-chalcones with relatively lower rate.

We also recommend Trading Suppliers and Manufacturers of ethyl 2-broMo-2-(2-fluorophenyl)acetate (cas 100638-28-6). Pls Click Website Link as below: cas 100638-28-6 suppliers

Prev:Synthesis, characterization and pharmacological activity of 4-{[1-substituted aminomethyl-4-arylideneamino-5-sulfanyl-4,5-dihydro-1H-1,2,4-triazol-3-yl]methyl}-2H-1,4-benzothiazin-3(4H)-ones
Next:Novel white light emitting dysprosium oxalate nanocrystals: Competing luminescence quenching by the features of Dy-Oxalate layered structure)