New 4,4-bis(trifluoromethyl)-4H-1,3,2-benzodioxaphosphinine 2-oxides(sulfides)
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Add time:08/05/2019 Source:sciencedirect.com
Substituted α,α-bis(trifluoromethyl)salicylic alcohols react with dichlorido(thio)phosphates in the presence of NEt3 to afford 2-alkoxy-4,4-bis(trifluoromethyl)-4H-1,3,2-benzodioxaphosphinine 2-oxide(sulfides) in high yields. The latter can be of interest as potential cholinesterase inhibitors.
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