Cyclopropanone equivalents from 3-chloropropionic acid 1-piperidino-1-trimethylsilyloxycyclopropane

Add time:08/06/2019    Source:sciencedirect.com

1-Piperidino-1-trimethylsilyloxycyclopropane and the corresponding 1-hydroxy-1-piperidinocyclopropane are conveniently perpared from the piperidide of 3-chloropropionic acid. Reactions of these cyclopropanone equivalents with various nucleophiles are described.

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