Zinc(II)-chloride induced thioalkylation of aluminium enolates; Enantioselective synthesis of estradiol-3-methyl-17-tert-butyl diether

Add time:08/07/2019    Source:sciencedirect.com

Zinc(II)-chloride induced thioalkylation of the aluminium enolate 6 generated by conjugate reduction of the enone 5 leads - directly or via its trimethylsilylenol ether 6 - to alkylated hydrindanones 10 which are important intermediates in the synthesis of 19-norsteroids such as the title compound estradiol-3-methyl-17-tert-butyl diether 12.

We also recommend Trading Suppliers and Manufacturers of TERT-BUTYL (1S,9S)-6,10-DIOXO-9-PHTHALIMIDOOCTAHYDROPYRIDAZO[1,2-A][1,2]DIAZEPINE-1-CARBOXYLATE (cas 106928-72-7). Pls Click Website Link as below: cas 106928-72-7 suppliers

Prev:Measurements of the density and viscosity of binary mixtures of (hyper-branched polymer, B-H2004 + 1-butanol, or 1-hexanol, or 1-octanol, or methyl tert-butyl ether)
Next:Reduction of l)