Inhibition of intestinal bile acid absorption improves cholestatic liver and bile duct injury in a mouse model of sclerosing cholangitis
-
Add time:08/13/2019 Source:sciencedirect.com
Background and AimsApproximately 95% of bile acids (BAs) excreted into bile are reabsorbed in the gut and circulate back to the liver for further biliary secretion. Therefore, pharmacological inhibition of the ileal apical sodium-dependent BA transporter (ASBT/SLC10A2) may protect against BA-mediated cholestatic liver and bile duct injury.
We also recommend Trading Suppliers and Manufacturers of TAUROHYODEOXYCHOLIC ACID SODIUM SALT (cas 110026-03-4). Pls Click Website Link as below: cas 110026-03-4 suppliers
Prev:Therapeutic effects of an oral adsorbent on acute dextran sulphate sodium-induced colitis and its recovery phase in rats, especially effects of elimination of bile acids in gut lumen
Next:Influence of dietary bile acids on formation of bile acids in rat) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Competition in liver transport between chenodeoxycholic acid and ursodeoxycholic acid as a mechanism for ursodeoxycholic acid and its amidates' protection of liver damage induced by chenodeoxycholic acid08/15/2019
- Influence of dietary bile acids on formation of bile acids in rat08/14/2019
- Therapeutic effects of an oral adsorbent on acute dextran sulphate sodium-induced colitis and its recovery phase in rats, especially effects of elimination of bile acids in gut lumen08/12/2019
- Bile salt deconjugation and BSH activity of five bifidobacterial strains and their cholesterol co-precipitating properties08/11/2019
- Individual serum bile acid profiling in rats aids in human risk assessment of drug-induced liver injury due to BSEP inhibition08/10/2019
- Turnover of bile acids in liver, serum and caecal content by high-fat diet feeding affects hepatic steatosis in rats08/09/2019
- Hepatocyte peroxisome proliferator-activated receptor alpha regulates bile acid synthesis and transport08/08/2019
- ApoE is a major determinant of hepatic bile acid homeostasis in mice08/07/2019
- Composition and aggregational forms of biliary lipids in human bile after short-term administration of Taurohyodeoxycholic acid08/06/2019
-
Health and Chemical more >