Synthesis of a potential inhibitor of UDP-glucuronosyltransferase

Add time:08/07/2019    Source:sciencedirect.com

A convenient synthesis of phosphonomethyl 1-O-(2,2,2-triphenyl)ethyl-α-D-gluco-2-heptulopyranosiduronate (2) is presented. The target compound proved to be an inhibitor of UDP-glucuronosyltransferase in vitro.

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