A semi-molten mixture of hexadecyltributylphosphonium bromide and potassium fluoride in the synthesis of organofluorine compounds

Add time:08/07/2019    Source:sciencedirect.com

A facile and effective reagent system comprising of a semi-molten mixture of hexadecyltributylphosphonium bromide and potassium fluoride has been developed and its scope has been investigated in nucleophilic fluoride exchange with various organohalides. This simple and convenient reagent system provides organofluorine compounds in high yields even with haloesters in which fluoride catalysed elimination is also feasible.

We also recommend Trading Suppliers and Manufacturers of 3-Fluoro-4-bromobenzyl bromide (cas 127425-73-4). Pls Click Website Link as below: cas 127425-73-4 suppliers

Prev:Transition metal complexes of tris(aminomethyl)phosphine oxide (tampo) – Thermodynamic and X-ray diffraction studies
Next:A simple and efficient synthesis of enantiomeric (3aRS,4RS,6aSR)-4-hydroxy-3,3a,4,6a-tetrahydro-1H-cyclopenta[c]furan-1-ones)