Groove selectivity in the interaction of 9-aminoacridine-4-carboxamide (cas 106988-43-6) antitumor agents with DNA
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Add time:08/12/2019 Source:sciencedirect.com
Theoretical quantitative evaluation of the intercalative binding to DNA of the new antitumor drug 9-amino-acridine-4-carboxamide indicates that, in contradiction with a recently proposed model, the compound should show specificity for interaction with the major (and not minor) groove of GC sequences.
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