An enantioselective synthesis of (2S,3S)- and (2R,3S)-3-hydroxyleucine

Add time:08/07/2019    Source:sciencedirect.com

α-Bromo β-hydroxy ester 2 was prepared in a preparative scale by a 96 : 4 enantioselective aldol reaction of t-butyl bromoacetate with isobutyraldehyde and converted efficiently to either (2S,3S)- or (2R,3S)-3-hydroxyleucine (7 or 11).

We also recommend Trading Suppliers and Manufacturers of (2S,3S)-TRANS-2-METHYL-3-PHENYLOXIRANE- 2-METHANOL (cas 107033-44-3). Pls Click Website Link as below: cas 107033-44-3 suppliers

Prev:Efficient decolorization and detoxification of reactive orange 7 using laccase isolated from Paraconiothyrium variabile, kinetics and energetics
Next:Synthesis of cis-fused hexahydro-4aH-indeno[1,2-b]pyridines via intramolecular Ritter reaction and their conversion into tricyclic analogues of NK-1 and dopamine receptor ligands)