Trienediolates of hexadienoic acids in synthesis. synthesis of retinoic and nor-retinoic acids.

Add time:08/07/2019    Source:sciencedirect.com

Double deprotonation of either (E,E)-3-methyl-2,4-hexadienoic acid 2, or 4,6-dimethyldihydro-2-pyrone 3 generates apparently the same lithium trienediolate, which affords ω-hydroxy acids 9 on reaction with ketones 7. Hydroxy acids 9 are easily dehydrated to octatrienoic acids 5, which are structurally related to retinoic acid. Similarly, sorbic acid 1 leads to nor-retinoic acid analogs 6.

We also recommend Trading Suppliers and Manufacturers of Retinoic acid,2-(4-methoxyphenyl)-2-oxoethyl ester, 13-cis- (cas 127471-94-7). Pls Click Website Link as below: cas 127471-94-7 suppliers

Prev:Expression of HUMAN VEGF165 (cas 127464-60-2) in silkworm (Bombyx mori L.) by using a recombinant baculovirus and its bioactivity assay
Next:Thiourea complexes of zinc, cadmium and mercuric perchlorates, fluoborates and trifluoroacetates; their stability and composition studied by paper chromatography, using 35S-thiourea)