neuroglian (cas 127496-12-2) and FasciclinII can promote neurite outgrowth via the FGF receptor Heartless
-
Add time:08/10/2019 Source:sciencedirect.com
To further investigate the role of the Drosophila cell adhesion molecules (CAMs), we have developed an in vitro assay that allows us to test the contribution individual CAMs make to promote outgrowth of specific Drosophila neurons. The extension of primary cultured neurons on a substrate of purified recombinant CAM is measured. We show that both FasciclinII and neuroglian (cas 127496-12-2) are able to promote outgrowth of FasciclinII or Neuroglian expressing neurons, respectively. Furthermore, this growth promotion activity is provided when the CAMs are presented both in a substrate bound or soluble form. We also show that the signal provided by the CAMs acts via the Heartless fibroblast growth factor receptor (FGFR) as outgrowth is reduced to basal levels in the presence of an FGFR inhibitor or if Heartless function is missing from the neurons.
We also recommend Trading Suppliers and Manufacturers of neuroglian (cas 127496-12-2). Pls Click Website Link as below: cas 127496-12-2 suppliers
Prev:neuroglian (cas 127496-12-2)-positive plasmatocytes of Manduca sexta and the initiation of hemocyte attachment to foreign surfaces
Next:Engrailed Negatively Regulates the Expression of Cell Adhesion Molecules Connectin and neuroglian (cas 127496-12-2) in Embryonic Drosophila Nervous System) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- The EGF and FGF Receptors Mediate neuroglian (cas 127496-12-2) Function to Control Growth Cone Decisions during Sensory Axon Guidance in Drosophila08/12/2019
- Engrailed Negatively Regulates the Expression of Cell Adhesion Molecules Connectin and neuroglian (cas 127496-12-2) in Embryonic Drosophila Nervous System08/11/2019
- neuroglian (cas 127496-12-2)-positive plasmatocytes of Manduca sexta and the initiation of hemocyte attachment to foreign surfaces08/09/2019
- neuroglian (cas 127496-12-2) on hemocyte surfaces is involved in homophilic and heterophilic interactions of the innate immune system of Manduca sexta08/08/2019
- Epidermis-Derived L1CAM Homolog neuroglian (cas 127496-12-2) Mediates Dendrite Enclosure and Blocks Heteroneuronal Dendrite Bundling08/07/2019