Asymmetric organocatalytic N-nitroso-aldol reaction of oxindoles

Add time:07/12/2019    Source:sciencedirect.com

An organocatalytic enantioselective N-nitroso-aldol reaction of 2-oxindoles promoted by a cinchona alkaloid catalyst has been developed. The reaction shows exclusively N-selectivity, affording corresponding products with good to excellent yields (up to 100%) and moderate enantioselectivity. The regioselectivity of nitroso-aldol reaction being controlled by different cinchona catalysts was also observed.

We also recommend Trading Suppliers and Manufacturers of 3-{[methyl(nitroso)amino]methyl}benzonitrile (cas 98736-49-3). Pls Click Website Link as below: cas 98736-49-3 suppliers

Prev:Synthesis and biological evaluation of solubilized sulfonamide analogues of the phosphatidylinositol 3-kinase inhibitor ZSTK474
Next:Synthesis of new AB-type monomers for polybenzimidazoles from N-(4,5-dichloro-2-nitrophenyl)acetamide)