Double activation preparation of an acridinyl-isoxazolyl-lexitropsin (cas 110124-49-7)
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Add time:08/11/2019 Source:sciencedirect.com
The coupling of a sterically hindered acridinyl isoxazole ester directly to the amine group of a lexitropsin is significantly improved by double activation, using trimethylaluminum to activate the amine portion and samarium (III) chloride to enhance the carboxylate reactivity.
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