Intramolecular reductive amination strategy to the synthesis of (R)-N-Boc-2-hydroxymethylmorpholine, N-(3,4-dichlorobenzyl)(R)-2-hydroxymethylmorpholine, and (R)-2-benzylmorpholine

Add time:08/08/2019    Source:sciencedirect.com

A concise high yielding enantioselective synthesis of (R)-N-Boc-2-hydroxymethylmorpholine, N-(3,4-dichlorobenzyl)(R)-2-hydroxymethylmorpholine, and (R)-benzylmorpholine has been achieved by employing proline-catalyzed asymmetric α-aminooxylation of aldehyde and palladium-catalyzed intramolecular reductive amination of azido aldehyde as the key steps.

We also recommend Trading Suppliers and Manufacturers of 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE (cas 110167-20-9). Pls Click Website Link as below: cas 110167-20-9 suppliers

Prev:Aquamarine blue emitting silver nanoparticles as fluorescent sensor for melamine detection
Next:Relative content of gallic acid over 5-galloylquinic acid as an index for the baking intensity of oolong teas)