Iodine-mediated electrophilic tandem cyclization of 2-alkynylbenzaldehydes with anthranilic acid leading to 1,2-dihydroisoquinoline-fused benzoxazinones

Add time:08/09/2019    Source:sciencedirect.com

An efficient iodine-mediated electrophilic tandem cyclization of substituted 2-alkynylbenzaldehydes with anthranilic acids under basic medium leading to iodo-1,2-dihydroisoquinoline-fused benzoxazinones is presented. Success of the protocol for the reaction of substituted 2-alkynylbenzaldehydes with 2-aminobenzamides to furnish isoquinoline-fused quinazolinones is also described.

We also recommend Trading Suppliers and Manufacturers of N-(3-METHYLPHENYL)ANTHRANILIC ACID (cas 16524-22-4). Pls Click Website Link as below: cas 16524-22-4 suppliers

Prev:Affinity and kinetics study of anthranilic acids as HCA2 receptor agonists
Next:Synthesis and insecticidal evaluation of novel anthranilic diamides containing N-substitued nitrophenylpyrazole)