High expression of topoisomerase-II predicts favorable clinical outcomes in patients with relapsed small cell lung cancers receiving AMRUBICIN (cas 110267-81-7)
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Add time:08/08/2019 Source:sciencedirect.com
ObjectivesAmrubicin monotherapy is a treatment option for patients with relapsed small cell lung cancers (SCLCs). Topoisomerase-II (Topo-II) – a target of amrubicin – has been reported as a predictive or prognostic marker for chemosensitivity or outcomes in patients with various malignancies. Here, we investigated the prognostic role of Topo-II expression in patients with relapsed SCLCs who underwent amrubicin monotherapy.
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