Synthesis and insecticidal evaluation of novel N′-tert-butyl-N′-substitutedbenzoyl-N-5-chloro-6-chromanecarbohydrazide derivatives

Add time:07/14/2019    Source:sciencedirect.com

A series of novel N′-tert-butyl- N′-substitutedbenzoyl-N-5-chloro-6-chromanecarbohydrazide derivatives were synthesized, and their larvicidal activities against Oriental armyworm were evaluated. The results of bioassays indicated that most of these title compounds exhibit higher larvicidal activities than RH-5849, and several of them somewhat lower than the commercial insecticide tebufenozide. The larvicidal activities are strongly associated with the types and patterns of substitution on the benzene, and 3,5-dimethyl, 2-nitro-4-chloro and 3-methyl derivatives are most prominent in increasing activity. Toxicity assays indicated that these derivatives could induce a premature, abnormal, and lethal larval moult.

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