Novel nor-monoterpenoid indole alkaloids inhibiting glioma stem cells from fruits of Alstonia scholaris
-
Add time:08/19/2019 Source:sciencedirect.com
BackgroundGlioblastoma multiforme (GBM) is a highly aggressive and frequently recurrent malignant brain tumor, and to date, the clinically effective drugs against GBM remain scarce. Natural products play an important role in drug discovery, and might be the resource of antitumor agents for GSCs. Alstonia scholaris (L.) R. Br. is rich in monoterpenoid indole alkaloids (MIAs) and used extensively for treatment of tumor in the traditional medicine system of Asia.
We also recommend Trading Suppliers and Manufacturers of S(-)-SCH-23388 NOR METHYL- HCL (cas 107128-79-0). Pls Click Website Link as below: cas 107128-79-0 suppliers
Prev:7β-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues
Next:Density functional theory and two-dimensional correlation polarized infrared spectroscopy studies on the anti-ferroelectric liquid crystal (1-methylheptyl)4-(4′-decyloxy-4-biphenyl) oxymethylene benzoate) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- 7β-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues08/18/2019
- C-3 halo and 3-methyl substituted 5′-nor-3-deazaaristeromycins: Synthesis and antiviral properties08/17/2019
- Graphene nanoplatelets in potentiometry: A nanocomposite carbon paste and PVC based membrane sensors for analysis of Vilazodone HCl in plasma and milk samples08/16/2019
- Methyl fluoroalkanoate as methyl-transferring reagent. Unexpected participation of BAl2 (SN2) mechanism in the reaction of methyl 2,3,3,3-tetrafluoro-2-methoxypropanoate with amines08/15/2019
- Catalytic conversion of duckweed to methyl levulinate in the presence of acidic ionic liquids08/14/2019
- In-vitro, ex-vivo, and in-vivo evaluation of buprenorphine HCl release from an in situ forming gel of PLGA-PEG-PLGA using N‑methyl‑2‑pyrrolidone as solvent08/13/2019
- 26- and 27-Methyl groups of 2-substituted, 19-nor-1α,25-dihydroxylated vitamin D compounds are essential for calcium mobilization in vivo08/12/2019
- Nor-limonoid and homoisoanticopalane lactones from methyl isoanticopalate08/11/2019
- Diastereoselective and enantioselective preparation of nor-mevaldic acid surrogates through desymmetrisation methodology. Enantioselective synthesis of (+) and (−) nor-mevalonic lactones08/10/2019
