3-(1-Arylsulfonylalkyl)-7-azaindoles as precursors of vinylogous imine intermediates for hetero-Michael addition reactions

Add time:07/11/2019    Source:sciencedirect.com

Michael addition of hetero-nucleophiles to active vinylogous imine intermediates generated in situ from 3-(1-arylsulfonylalkyl)-7-azaindoles has been described. This new strategy provides a facile and efficient approach to valuable 3-alkyl substituted 7-azaindole derivatives containing heteroatoms in high yields.

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