The effects of the herbicide 2,4-dichlorophenyl-p-nitrophenyl ether (NIT) on serum thyroid hormones in adult female mice

Add time:07/13/2019    Source:sciencedirect.com

The administration of the herbicide 2,4-dichlorophenyl-p-nitrophenyl ether (nitrofen; NIT) to adult female mice by i.p. injection at doses of 500 and 1000 mgkgday for 3 days, reduced serum thyroxine (T4) levels. T4 levels were reduced in the high-dosage group by 60% of the control and by 20% in the low-dose group. Serum triiodothyronine (T3) levels were relatively unaffected by NIT treatment at either dose. The animals appeared euthyroid, as body weights were unaffected even though T4 levels were reduced. Liver weights were slightly higher as a result of NIT exposure at both 500 and 1000 mgkgday.

We also recommend Trading Suppliers and Manufacturers of N-(2,4-DICHLOROPHENYL)-5-METHYL-1-(4-NITROPHENYL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE (cas 306977-09-3). Pls Click Website Link as below: cas 306977-09-3 suppliers

Prev:Novel thiosemicarbazide derivatives with 4-nitrophenyl group as multi-target drugs: α-glucosidase inhibitors with antibacterial and antiproliferative activity
Next:Toxicologic studies on 2,4-dichlorophenyl-p-nitrophenyl ether)