Regular ArticleINSULINOTROPIC ACTION OF NOVEL SUCCINIC ACID ESTERS
-
Add time:08/11/2019 Source:sciencedirect.com
The insulinotropic action of several new esters of succinic acid was assessed in isolated rat islets incubated in the presence of 7mM D-glucose. An efficient secretory response was observed with the monobenzyl, monoisopropyl, monoallyl, monopropyl, monoethyl, monobutyl, dibutyl, dipropyl and diallyl esters of succinic acid. This indicates that it is possible to design esters of succinic acid which act as insulin secretagogues, while avoiding the undesirable generation of methanol that otherwise results from the use of either the monomethyl or dimethyl ester of this dicarboxylic acid.
We also recommend Trading Suppliers and Manufacturers of SUCCINIC ACID MONOBENZYL ESTER (cas 103-40-2). Pls Click Website Link as below: cas 103-40-2 suppliers
Prev:Tautomeric and non-tautomeric N-substituted 2-iminobenzimidazolines as new lead compounds for the design of anti-influenza drugs: An in vitro study
Next:Monocomponent hexa- and dodecaethylene glycol succinyl-tocopherol esters: Self-assembly structures, cellular uptake and sensitivity to enzyme hydrolysis) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Factors Affecting Conformation of (R,R)-Tartaric Acid Ester, Amide and Nitrile Derivatives. X-Ray Diffraction, Circular Dichroism, Nuclear Magnetic Resonance and Ab Initio Studies08/14/2019
- New propanoyloxy derivatives of 5β-cholan-24-oic acid as drug absorption modifiers08/13/2019
- Monocomponent hexa- and dodecaethylene glycol succinyl-tocopherol esters: Self-assembly structures, cellular uptake and sensitivity to enzyme hydrolysis08/12/2019
-
Health and Chemical more >