Chemical constituents from Mentha canadensis

Add time:08/11/2019    Source:sciencedirect.com

Phytochemical investigation on Mentha canadensis led to the isolation of two new compounds, 3,4-dihydro-3,6,7-trihydroxy-2(1H)-quinolinone (1), (E)-2-methoxy-2- oxethyl-3-(4-hydroxyphenyl) acrylate (2), along with nine known phenolic compounds, syringic acid (3), p-coumaric acid (4), esculetin (5), methyl rosmarinate (6), nepetoidin B (7), syringaresinol (8), methyl ester of caffeoyl glycollic acid (9), 2″,3″-diacetylmartynoside (10) and bracteanolide A (12). Additionally, cis-3-[2-[1-(3,4-dihydroxyphenyl)-1-hydroxymethyl]-1,3-benzodioxol-5-yl]-(E)-2-propenoic acid (11), which was isolated as a natural product for the first time. All these compounds were reported for the first time from this species, and their structures were elucidated by spectroscopic techniques. Compound 11 may be a useful chemotaxonomic marker for M. canadensis. The p-coumaric acid derivatives identified in the present investigation may have chemotaxonomic significance at the generic level.

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