Synthesis of new carbocyclic oxetanocin analogues
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Add time:08/12/2019 Source:sciencedirect.com
Carbocyclic oxetanocin analogues containing 3-fluoro or 3-hydroxy cyclobutyl moieties and different natural bases, have been prepared from the olefinic precursors either by direct fluoro-iodination (AgF-I2) or by DAST fluorination of the bromhydrin. The latter allowed the synthesis of the corresponding phosphonate derivatives as well.
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