Stereoselective cyclopropanation of α-bromochalcone with diethyl malonate promoted by K2CO3
-
Add time:08/12/2019 Source:sciencedirect.com
A new Michael-initiated cyclopropanation reaction using α-bromochalcones as Michael acceptor was developed. Compared to previous works using arylidenemalonates as Michael acceptor, this novel protocol could improve the synthesis of trans-isomers of diethyl 2-benzoyl-3-phenyl-cyclopropane-1,1-dicarboxylates. More importantly, this method also provided the first access to the cis-isomers of these densely substituted cyclopropanes with the Michael-initiated ring closure (MIRC) strategy, albeit with a poor diastereoselectivity.
We also recommend Trading Suppliers and Manufacturers of DIETHYL 4-NITROPHENYL MALONATE (cas 10565-13-6). Pls Click Website Link as below: cas 10565-13-6 suppliers
Prev:Photoisomerization of cyclopentene-based β-(2-furanyl)- and β-(2-thienyl)enones
Next:Crown ether derived from d-glucose as an efficient phase-transfer catalyst for the enantioselective Michael addition of malonates to enones) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Asymmetric Michael addition of malonates to unsaturated ketones catalyzed by rare earth metal complexes bearing phenoxy functionalized chiral diphenylprolinolate ligands08/16/2019
- Thermal decomposition of 2-(4-nitrophenyl)- and 2-(2,4-dinitrophenyl)malonic acids and derivatives☆08/15/2019
- New and efficient synthesis of dialkyl 2-[1-p-nitrophenyl-2-(alkylamino)-2-oxoethyl]malonates08/14/2019
- Crown ether derived from d-glucose as an efficient phase-transfer catalyst for the enantioselective Michael addition of malonates to enones08/13/2019
-
Health and Chemical more >
-
Related Products
- 4-Nitrophenyl 2-(furfurylsulfinyl)acetic acid
- 4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate
- 4-Nitrophenyl 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranoside
- 4-Nitrophenyl 2-acetamido-2-deoxy-alpha-D-galactopyranose
- 4-Nitrophenyl 4-methoxybenzoate
- 4-Nitrophenyl 4-O-(2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosyl)-2,3,6-tri-O-acetyl-beta-D-thioglucopyranoside
- 4-Nitrophenyl alpha-D-galactopyranoside
- 4-Nitrophenyl alpha-D-glucopyranoside
- 4-Nitrophenyl alpha-L-arabinopyranoside
- 4-Nitrophenyl beta-D-cellobioside