Convenient synthesis of l-proline benzyl ester

Add time:08/12/2019    Source:sciencedirect.com

Mesylates or tosylates of δ-hydroxy-l-norvaline esters spontaneously afford l-proline esters upon exposure to aqueous buffer in near quantitative yield. This novel reaction has led to the development of a simple route to optically active proline esters.

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